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This unique fixed combination is designed to deeply penetrate plaque biofilm and kill bacteria that can lead to gingivitis


With the help of our unique formulation1 that includes the 4 ESSENTIAL Oils (eucalyptol, menthol, methyl salicylate, thymol) LISTERINE® Antiseptic penetrates plaque biofilm killing germs in virtually 100% of the mouth.1-4 Unique to LISTERINE® Brand Antiseptic, this fixed combination of the 4 ESSENTIAL Oils formula is not offered by any other nationally branded rinses.

To help patients fight the bacteria that can lead to gingivitis, recommend a LISTERINE® Brand rinse with the 4 ESSENTIAL Oils formula, like LISTERINE® COOL MINT®, for a complete oral care routine.

See our science up close

Watch the video below to learn about the germ-killing power of our Antiseptic products with the unique formulation of 4 ESSENTIAL Oils.1-54EO Video

Listerine 4 Essential Oils

References: 1. DePaola LG, Spolarich AE. Safety and efficacy of antimicrobial mouthrinses in clinical practice. J Dent Hygiene. 2007;81(special suppl):13-25. 2. Sharma N, Charles CH, Lynch MC, et al. Adjunctive benefit of an essential oil-containing mouthrinse in reducing plaque and gingivitis in patients who brush and floss regularly: a six-month study. J Am Dent Assoc. 2004;135(4):496-504. 3. Fine DH, Furgang D, Lieb R, Korik I, Vincent JW, Barnett ML. Effects of sublethal exposure to an antiseptic mouthrinse representative plaque bacteria. J Clin Periodontol. 1996;23(5):444-451. 4. Ricci-Nittel D, Fourre T. In vivo evaluation of antimicrobial activity of an essential-oil mouthrinse. Presented at: General Session of the International Association for Dental Research; March 16-19, 2011; San Diego, CA. Oral Session. 5. Pan PC, Harper S, Ricci-Nittel D, Lux R, Shi W. In-vitro evidence for efficacy of antimicrobial mouthrinses. J Dent. 2010;38(suppl 1):S16-S20.