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A Comparison of the Effects of 2 Commercially Available Nonprescription Mouthrinses on Salivary Flow Rates and Xerostomia1

- Kerr AR, Katz RW, Ship JA. A comparison of the effects of 2 commercially available nonprescription mouthrinses on salivary flow rates and xerostomia. Quintessence Int. 2007;38(705):41-48.

Objective

To determine if 2 commercial mouthrinses, 1 alcohol-based (LISTERINE® COOL MINT®) and 1 nonalcohol-based (Act® Anticavity Fluoride Mouthwash—Alcohol Free, Mint), affect salivary flow and symptoms of dry mouth in nonxerostomic adults (N=20).

Methodology

Observer-blinded, randomized, crossover study of nonxerostomic subjects (aged 18-85 years).

Results

After 1 week of mouthrinse use, combined data (before and after crossover) revealed no significant differences in flow rates between groups (P>0.05).

Conclusion

“There were no differences in objective or subjective measures of mouth dryness between alcohol- and nonalcohol-containing mouthrinses after 1 week in nonxerostomic subjects.”*

*LISTERINE® Antiseptic is not indicated for use in the treatment of xerostomia.
†Nonalcohol based.

Reference: 1. Kerr AR, Katz RW, Ship JA. A comparison of the effects of 2 commercially available nonprescription mouthrinses on salivary flow rates and xerostomia.Quintessence Int. 2007;38(705):41-48.